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August 9, 2025

HIV patient treatment adherence trajectories in first 24-months post-ART initiation among adults: an electronic health records cohort from South Africa.

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Authors

ADArmstrong DzombaKSKhumbo ShumbaCNCornelius Nattey

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Overview

Cohort study reveals adherence patterns in adults starting ART in South Africa, indicating key demographic influences on treatment success.

Key Points

  • Mean treatment adherence drops to 47% between months 13 and 24 for adults on ART.
  • Approximately 85% of patients with low adherence in the first year fail to improve in the following year.
  • Men are less likely than women to achieve optimal adherence levels post-ART initiation.
  • Adults aged 25 and older show a higher likelihood of improving adherence compared to younger patients.

Cite This Study

Dzomba et al. (2025) studied this question.

synapsesocial.com/papers/689dfe97d61984b91e13c1dchttps://doi.org/10.1097/qai.0000000000003736
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adherence to Antiretroviral Therapy among Patients with Human Immunodeficiency Virus: Rates and Determinants2025
  2. 2Ten-year outcomes of antiretroviral therapy: a retrospective cohort study in Tshwane district, South Africa2025
  3. 3Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana2026
  4. 4Rates of adherence, adherence measurement, and support services for children and adolescents living with HIV followed in global sites of the International Epidemiology Databases to Evaluate AIDS (IeDEA)2025
  5. 5Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa2025