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June 20, 2026BMC Infectious DiseasesOpen Access

Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana

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Authors

ENEric NyarkoIKIrene A. KretchyGAGrace Lovia Allotey-Babington

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Overview

Cross-sectional study quantifies ART adherence in people living with HIV, suggesting targeted interventions are needed.

Key Points

  • This research aims to quantify adherence to antiretroviral therapy (ART) among people living with HIV at Pantang Hospital.
  • Cross-sectional design assessing ART adherence among 151 participants at Pantang Hospital, Ghana.
  • Data collected through interviewer-administered questionnaires on sociodemographic characteristics and adherence behaviors.
  • Six machine learning models were applied to identify predictors of non-adherence and compare model performance.
  • Poor adherence to ART was found, with 66.9% forgetting to take medication and 64.2% exhibiting carelessness.
  • Elastic Net regression was the top-performing model for predicting adherence.
  • Key predictors of non-adherence included not taking medication over the past weekend (utility estimate 0.3471, 95% CI 0.2292–0.4650) and missing medication 6–10 times in the past week (utility estimate 0.2693, 95% CI 0.1538–0.3848).

Cite This Study

Nyarko et al. (2026) studied this question.

synapsesocial.com/papers/6a362e91db0793dc1a536402https://doi.org/10.1186/s12879-026-13836-z
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