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August 9, 2025

Rewiring the scar: translational advances in cardiac fibrosis.

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Authors

TTThị Ngọc Huyền TrầnPLPhuoc Hoang LeSYSeonbu Yang

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Overview

This review highlights the molecular drivers and emerging therapies for cardiac fibrosis, suggesting a shift towards precision medicine.

Key Points

  • Cardiac fibrosis is a key factor in heart failure and involves complex cellular mechanisms.
  • Emerging therapies include small-molecule drugs and cell-based approaches showing promise in preclinical studies.
  • Diagnostic innovations like advanced imaging and biomarker panels are crucial for understanding cardiac fibrosis.
  • Translational methods incorporating precision medicine may enhance personalized treatment strategies for patients.

Cite This Study

Trần et al. (2025) studied this question.

synapsesocial.com/papers/689dfe97d61984b91e13bf1chttps://doi.org/10.4196/kjpp.25.160
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Therapeutic Targets for Myocardial Fibrosis: A Comprehensive Review of Current and Emerging Approaches2025
  2. 2Intercellular Targetable Mechanistic Interface for Cardiac Fibrosis2026
  3. 3Targeting Inflammation and Fibrosis in Cardiovascular Disease: Emerging Mechanisms and Therapies2025 · 17 citations
  4. 4In Vivo Targeted Reprogramming of Cardiac Fibroblasts for Heart Regeneration: Advances and Therapeutic Potential2025 · 5 citations
  5. 5Transcriptome fingerprinting of aberrant fibroblast activation unlocks effective therapeutics to tackle cardiac fibrosis2025 · 3 citations