August 8, 2025

Circulating microRNA-1 as a diagnostic biomarker for acute myocardial infarction: a meta-analysis.

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Discussion

Meta-analysis shows microRNA-1 has 78% sensitivity and 85% specificity for acute myocardial infarction, indicating potential clinical utility.

MicroRNA-1 demonstrates strong diagnostic performance for acute myocardial infarction (AMI).
The meta-analysis pooled sensitivity at 78% and specificity at 85% for diagnosing AMI.
Analyzed data from 11 studies involving 894 AMI patients and 600 controls using Stata15.0 software.
Finding supports microRNA-1 as a reliable biomarker that could enhance AMI diagnosis alongside other tests.

Li et al. (2025) studied this question.

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Meta-analysis shows microRNA-1 has 78% sensitivity and 85% specificity for acute myocardial infarction, indicating potential clinical utility.