Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 4, 2025

Figure 1 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes

View Full Paper
Ask AI
Bookmark
Share

Authors

DMDimitrios MathiosNNNoushin NiknafsAAAkshaya V. Annapragada

Discussion

Loading...

Member takes

Overview

This research demonstrates cfDNA's potential in identifying brain cancer in patients, suggesting new paths for liquid biopsies.

Key Points

  • Main finding shows that cfDNA fragmentation is altered in patients with brain cancer compared to healthy individuals.
  • The study highlights the influence of the immune-suppressive microenvironment on cfDNA release from lymphocytes and tumor cells.
  • Methods include analyzing cfDNA from patients and evaluating the role of brain tumor microenvironments in cfDNA integrity.
  • These findings could impact early detection of brain cancer and improve non-invasive diagnostic techniques.

Cite This Study

Mathios et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0965https://doi.org/10.1158/2159-8290.29819638
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Figure 5 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  2. 2Data from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  3. 3Figure 4 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  4. 4Table 1 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  5. 5Cell-free DNA fragmentomics in cancer2025 · 52 citations