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August 4, 2025

Figure 5 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes

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Authors

DMDimitrios MathiosNNNoushin NiknafsAAAkshaya V. Annapragada

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Overview

Analysis of cfDNA fragmentation reveals correlations in tumor types and immune cell subpopulations in patients with HGGs.

Key Points

  • The study investigates cfDNA fragmentation origins in high-grade gliomas (HGGs) using DECIFER analyses.
  • It finds significant Pearson R correlations between TFBSs and tumor types, impacting diagnostics.
  • Data include immune cell subpopulations, brain tumor tissue, and various cancers like lung adenocarcinoma and hepatocellular carcinoma.
  • Understanding cfDNA fragmentation can enhance brain cancer detection and aid in treatment strategies.

Cite This Study

Mathios et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0963https://doi.org/10.1158/2159-8290.29819626
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Figure 1 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025 · 1 citations
  2. 2Figure 4 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  3. 3Data from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  4. 4Figure 3 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025
  5. 5Figure 2 from Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes2025