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July 28, 2025Food Science & NutritionOpen Access

The Effects of Probiotics Consumption on Blood Pressure, Lipid Profile, Glycemic Indices, and Inflammatory Parameters in Overweight and Obese Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

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Authors

SSSafa Sefidgari‐AbrasiMRMarziyeh Rahimiyan‐HeravanVAVahid Amiran

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Overview

Systematic review analyzes probiotics' effects on lipid profile and blood pressure in obesity, suggesting potential benefits.

Key Points

  • Probiotic supplementation shows a slight beneficial effect on blood pressure and lipid metabolism in overweight individuals.
  • A meta-analysis of 26 randomized controlled trials included 1755 adults with overweight or obesity and assessed various metabolic factors.
  • Systolic blood pressure showed a small reduction, while fasting glucose and lipid levels, such as total cholesterol, also improved.
  • Further research is needed to confirm probiotics' role in mitigating cardiovascular risk factors due to the limited scope of current findings.

Cite This Study

Sefidgari‐Abrasi et al. (2025) studied this question.

synapsesocial.com/papers/689a0939e6551bb0af8ce92dhttps://doi.org/10.1002/fsn3.70434
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effects of probiotic supplementation on cardiometabolic health in patients with prediabetes: a systematic review, meta-analysis, and GRADE assessment2025
  2. 2Correction to “The Effects of Probiotics Consumption on Blood Pressure, Lipid Profile, Glycemic Indices, and Inflammatory Parameters in Overweight and Obese Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials”2025
  3. 3Probiotics and Cognitive-Related Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses of Randomized Controlled Trials2025
  4. 4Effects of a Probiotic Formulation Based on SF68, Phytosterols, and 6S‐5‐Methyltetrahydrofolic Acid on Body Composition, Biochemical Parameters, Gut Microbiota, and Gastrointestinal and General Symptoms of Overweight/Obese Subjects: The PrObesity Study2025
  5. 5Effects of Probiotic and Synbiotic Supplementation on Glycemic Indices in Adult Individuals with Prediabetes and Type 2 Diabetes Mellitus: A Grade-Assessed Systematic Review and Dose–Response Meta-analysis of RCTs2025 · 14 citations