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July 18, 2026JACC Case ReportsOpen Access

Rest and GDMT enable return-to-play for a professional athlete with PVCs and suspected myocarditis.

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Population

1 33-year-old male professional football player presenting for return-to-play evaluation of premature…

Design

Case_report

Key result

A 33-year-old professional football player with PVCs and possible subacute myocarditis was managed with 2 to 3 months of rest and guideline-directed medical therapy to facilitate return-to-play.

Authors

CPCharlotte PirquetDUDaniel UnderbergBOBrian Osler

Discussion

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Overview

Supports conservative rest and GDMT for return-to-play in athletes with myocarditis; extends real-world application of guidelines.

Key Points

  • This case examines the complexities in return-to-play decisions for athletes experiencing arrhythmias.
  • Evaluated a 33-year-old professional football player for premature ventricular contractions and chest pain.
  • Used electrocardiogram and cardiac magnetic resonance imaging for diagnosis.
  • Conducted risk stratification based on clinical findings and treatment options.
  • Identified fragmented R waves and PVCs on ECG, with late gadolinium enhancement suggesting possible myocarditis.
  • The player rested for 2 to 3 months and received guideline-directed medical therapy.
  • Risk assessment indicated increased risks due to late gadolinium enhancement yet supported a favorable risk profile based on other findings.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 33-year-old professional football player presenting with premature ventricular contractions and atypical chest pain, diagnosed with possible subacute myocarditis.
I
Intervention
Rest for 2 to 3 months and guideline-directed medical therapy
O
Outcome
Return-to-play (RTP) decision and risk stratification

This case highlights the complexity of return-to-play decisions in professional athletes with arrhythmias of uncertain etiology, emphasizing the need for individualized risk stratification integrating clinical data and imaging.

Cite This Study

Pirquet et al. (2026) conducted a case report in Premature ventricular contractions and possible subacute myocarditis (n=1). Rest and guideline-directed medical therapy was evaluated. A 33-year-old professional football player with PVCs and possible subacute myocarditis was managed with 2 to 3 months of rest and guideline-directed medical therapy to facilitate return-to-play.

synapsesocial.com/papers/6a5b38f68167787360d24df2https://doi.org/10.1016/j.jaccas.2026.108864
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ventricular arrhythmias in athletes: morphologic features and risk stratification of pathological myocardial substrate2026
  2. 2Catheter ablation of idiopathic premature ventricular contractions in athletes without structural heart disease: impact on arrhythmic burden and return to sport2026
  3. 3Syncope and Scar in a Former Elite Basketball Player2026
  4. 4Progressively complex exercise-induced ventricular arrhythmias unveiling catecholaminergic polymorphic ventricular tachycardia associated with a novel RYR2 variant in a competitive athlete: a case report2026
  5. 5Recurrent Pericarditis in a Rugby Player2026