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June 21, 2026International Journal of General MedicineOpen Access

Admission Uric Acid, Troponin, and C-Reactive Protein Levels and In-Hospital Mortality in Acute Stroke Patients

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Authors

ÖYÖmer YüceerAVAbdussamed Vural

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Overview

Retrospective study evaluates biomarkers associated with in-hospital mortality in acute stroke patients, suggesting supplementary use for risk assessment.

Key Points

  • This study aimed to evaluate the links between admission levels of serum uric acid, troponin, and C-reactive protein and in-hospital mortality in acute stroke patients.
  • Retrospective single-center study of 403 adults with acute ischemic or hemorrhagic stroke between January 2019 and January 2022.
  • Data on demographics, comorbidities, and admission lab findings were collected from electronic records.
  • Univariate and multivariable logistic regression analyses were conducted to identify predictors of in-hospital mortality.
  • 16.6% of patients died during hospitalization, with non-survivors showing significantly higher levels of SUA, troponin, and CRP (p< 0.001).
  • Multivariable analysis identified advanced age (OR: 1.07), troponin >14 ng/L (OR: 2.23), CRP >5 mg/L (OR: 2.93), and SUA >7 mg/dL (OR: 1.93) as independent predictors of in-hospital mortality.
  • CRP displayed the highest discriminatory performance (AUC: 0.77), while troponin and SUA showed limited ability (AUC: 0.67 and 0.66, respectively).

Cite This Study

Yüceer et al. (2026) studied this question.

synapsesocial.com/papers/6a377fb224f042ddf4c5a063https://doi.org/10.2147/ijgm.s611009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stratifying Neurological Severity in Acute Ischemic Stroke: The Independent and Combined Prognostic Value of Admission D-Dimer and High-Sensitivity C-Reactive Protein2025
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  3. 3Predictive ability of cardiac biomarkers for early risk stratification and 3-month functional outcomes after reperfusion therapy in acute ischemic stroke2026
  4. 4Role of Metabolic and Inflammatory Biomarkers in Acute Stroke Patients Admitted in a Tertiary Care Hospital: Clinical Correlation of Lipid Profile, LDH, CPK, CRP, and HbA1c2025
  5. 5Diagnostic Biomarkers for Risk Estimation of In-Hospital and Post-Discharge Cardiovascular Mortality in ST-Segment Elevation Myocardial Infarction (STEMI) Patients2025 · 2 citations