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June 12, 2026European Journal of Preventive CardiologyOpen Access

Both groups demonstrated comparable improvements in muscular strength and exercise capacity parameters, with no significant between-group differences.

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Why the study?

Does eccentric resistance training improve muscular strength and exercise capacity compared to conventional training in patients with HFrEF?

Population

31 patients with heart failure with reduced ejection fraction (HFrEF)

Comparison

Eccentric and eccentric overload training… vs Standard care consisting of conventional…

Design

RCT, randomized

Follow-up

15 weeks

Authors

WHW HensLCL De CockSNS Naessens

Discussion

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Overview

Eccentric resistance training offers a comparable option to cardiotraining for HFrEF; extends rehabilitation choices with RCT support.

Key Points

  • This research aims to assess the effectiveness of eccentric resistance training compared to traditional cardiotraining in HFrEF patients.
  • 31 HFrEF patients were randomized into an intervention group emphasizing eccentric training and a control group engaging in standard training.
  • Participants completed training three times a week for approximately 50 minutes over 15 weeks.
  • Primary outcomes evaluated included muscular strength and exercise capacity after the training period.
  • Both groups showed comparable improvements in muscular strength and exercise capacity.
  • No significant between-group differences were found in intention-to-treat or sensitivity analyses.
  • Anthropometric parameters remained unchanged, indicating similar safety profiles.

Structured PICO

Does eccentric resistance training improve muscular strength and exercise capacity compared to conventional training in patients with HFrEF?

P
Population
31 patients with heart failure with reduced ejection fraction (HFrEF)
I
Intervention
Eccentric and eccentric overload training combined with limited treadmill-based moderate intensity cardiotraining (3 times/week, ~50 minutes/session for 15 weeks)
C
Comparator
Standard care consisting of conventional resistance training and moderate intensity cardiotraining using both treadmill and cycle ergometer (3 times/week, ~50 minutes/session for 15 weeks)
O
Outcome
Changes in muscular strength and exercise capacity parameters after 15 weeks trainingsurrogate

Eccentric resistance training is a feasible and effective alternative to conventional cardiotraining in patients with HFrEF, yielding similar improvements in strength and exercise capacity with a lower metabolic load.

Cite This Study

Hens et al. (2026) studied this question.

synapsesocial.com/papers/6a2bd1386550ea4541ffe968https://doi.org/10.1093/eurjpc/zwag249.047
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of eccentric cycling training on aerobic and functional capacity in patients with heart failure: a randomised controlled trial2026
  2. 2Comparative effects of different strength training modalities in cardiac rehabilitation: preliminary results2026
  3. 3ACUTE CARDIOVASCULAR RESPONSE TO RESISTANCE TRAINING DURING CARDIAC REHABILITATION: EFFECT OF MUSCLES MASS USED IN PATIENTS WITH CHRONIC HEART FAILURE2026
  4. 4Effects of eccentric contraction-based resistance exercise on physical performance in chronic stroke patients: A randomized controlled trial.2025
  5. 5Combined strength training and aerobic training vs. aerobic training alone in patients with heart failure: a systematic review and meta-analysis2026