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June 12, 2026European Journal of Preventive CardiologyOpen Access

Comparison of different aerobic exercise modalities on echocardiographic variables in early cardiac rehabilitation

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Why the study?

Do different aerobic exercise modalities (short-HIIT, long-HIIT, MICT) improve echocardiographic variables in patients with stable CAD in early cardiac rehabilitation?

Population

24 patients with stable coronary artery disease (CAD) enrolled in phase II cardiac rehabilitation

Comparison

Short high-intensity interval training or long… vs Moderate-intensity continuous training for 6 weeks

Design

RCT, randomised to short-HIIT (n = 9), long-HIIT (n = 7) or MICT (n = 8)

Follow-up

6 weeks

Authors

LKL Fuertes KenneallyARA M R Agustin Manresa RocamoraLBL S B Laura Sarrion Brotons

Discussion

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Overview

Exercise modality may differentially affect ventricular remodeling in early CAD rehab; leaves open optimal protocol selection.

Key Points

  • To compare the effects of short-HIIT, long-HIIT, and MICT on echocardiographic variables in early cardiac rehabilitation.
  • 24 patients with stable CAD were randomized to short-HIIT, long-HIIT, or MICT.
  • Echocardiography was performed at baseline and after 6 weeks.
  • Mixed ANOVA models assessed time and time×group effects on echocardiographic variables.
  • LVEDV increased significantly for short-HIIT (p=0.038) and showed group interaction (p=0.039).
  • LVEDD increased only in MICT (interaction p=0.012).
  • TAPSE increased (p=0.030), and sPAP decreased markedly (p=0.001), indicating improved RV systolic performance.

Structured PICO

Do different aerobic exercise modalities (short-HIIT, long-HIIT, MICT) improve echocardiographic variables in patients with stable CAD in early cardiac rehabilitation?

P
Population
24 patients with stable coronary artery disease (CAD) enrolled in phase II cardiac rehabilitation
I
Intervention
Short high-intensity interval training (short-HIIT) or long high-intensity interval training (long-HIIT) for 6 weeks
C
Comparator
Moderate-intensity continuous training (MICT) for 6 weeks
O
Outcome
Echocardiographic variables including left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV), left and right ventricular end-diastolic diameter (LVEDD, RVEDD), left atrial volume indexed (LAVi), mitral annular tissue Doppler velocity (e'), E/e' ratio, tricuspid annular plane systolic excursion (TAPSE), LV ejection fraction (LVEF), and systolic pulmonary artery pressure (sPAP) at 6 weekssurrogate

Six weeks of cardiac rehabilitation drives rapid structural cardiac changes, with short-HIIT producing the most pronounced left ventricular volumetric remodeling compared to MICT.

Cite This Study

Kenneally et al. (2026) studied this question.

synapsesocial.com/papers/6a2bd11d6550ea4541ffe89ehttps://doi.org/10.1093/eurjpc/zwag249.160
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Time-Course of Physiological Adaptations to High-Intensity Interval Training-Based Cardiac Rehabilitation After Myocardial Infarction2026
  2. 2Pushing the limits: high-intensity training in cardiac rehabilitation - a single-center experience2026
  3. 3Cardiac rehabilitation in non-ischaemic cardiomyopathies: functional, psychosocial, and structural benefits compared with coronary artery disease2026
  4. 4Impact of different exercise training modalities on patient-reported outcomes in heart failure with reduced and preserved ejection fraction2026
  5. 5Cardiac rehabilitation outcomes in heart failure: insights from echocardiographic deformation parameters2026