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June 7, 2026Diabetes

1942-P: Hyperglycemia Metrics from Continuous Glucose Monitoring Are Independently Associated with Platelet Morphology in Adults with Type 1 Diabetes

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Population

301 adults with type 1 diabetes without established cardiovascular disease, median age 33.1, 44.5% men.

Design

Cross-sectional

Authors

MKMICHAL KULECKIDNDariusz NaskrętAKAdrian Kubicki

Discussion

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Overview

In adults with type 1 diabetes, cumulative hyperglycemic exposure measured by CGM is independently associated with altered platelet morphology, suggesting a potential link to cardiovascular risk.

Structured PICO

P
Population
301 adults with type 1 diabetes without established cardiovascular disease, median age 33.1, 44.5% men.
I
Intervention
Continuous glucose monitoring (CGM) to assess glucose profiles over 7-, 14-, and 30-day windows
O
Outcome
Platelet morphology indices (platelet large cell ratio, mean platelet volume, and platelet distribution width) measured from fasting blood samplessurrogate

In adults with type 1 diabetes, cumulative hyperglycemic exposure measured by CGM is independently associated with altered platelet morphology, suggesting a potential link to cardiovascular risk.

Cite This Study

KULECKI et al. (2026) studied this question.

synapsesocial.com/papers/6a250ce97def13d035e1d252https://doi.org/10.2337/db26-1942-p
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 11929-P: Assessing Glycemic Variability by Continuous Glucose Monitoring: Implications for Prediabetes Subtypes and Potential Cardiovascular Risk2026
  2. 22184-P: CGM-Derived Measures in Relation to 10-Year CVD Risk in Adults without Diabetes2026
  3. 32962-LB: CGM Metrics and Cardiovascular and Mortality Outcomes in Type 2 Diabetes: Data from the GRADE-CGM Substudy2026
  4. 41038-OR: Poor Correlation between Hypoglycemic Symptoms and Heart Rate Response in Sensor-Detected Hypoglycemia in T2D: Hypo-METRICS Study2026
  5. 52983-LB: Trajectories of Risk Factors among Participants with Long-Duration Type 1 Diabetes2026