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This review aims to explore the multifaceted nature and pharmacological potential of glucagon-like peptide-1 (GLP-1).

September 30, 2019Molecular MetabolismOpen Access

Glucagon-like peptide 1 (GLP-1)

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Review discusses GLP-1's metabolic functions and therapeutic uses in diabetes and obesity, suggesting broad implications.

This review aims to explore the multifaceted nature and pharmacological potential of glucagon-like peptide-1 (GLP-1).
Overview of GLP-1 functions and pharmacology
Discussion of GLP-1 receptor agonists in diabetes and obesity treatment
Analysis of GLP-1's impact on various metabolic and neuroprotective effects.
GLP-1 stimulates insulin secretion and decreases gastric emptying, aiding in glucose regulation.
It shows cardio- and neuroprotective benefits, with implications for learning and memory.
GLP-1 receptor agonists are effective for type-2 diabetes management and are under evaluation for obesity treatment.

Müller et al. (2019) studied this question.

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