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January 24, 2026Journal of the American Heart AssociationOpen Access

CAV1 —A Susceptibility Gene for Atrial Fibrillation: The Impact of Coding and Noncoding Variants

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Key result

CAV1 was identified as an atrial fibrillation susceptibility gene, with 1 coding and 5 noncoding variants linked to increased risk and altered transcription factor activity.

Authors

KRKristin RädeckeDRD. RheinertALAnnette Löwen

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Cite This Study

Rädecke et al. (2026) studied this question. CAV1 was identified as an atrial fibrillation susceptibility gene, with 1 coding and 5 noncoding variants linked to increased risk and altered transcription factor activity.

synapsesocial.com/papers/697565e7d5e0d64addde817chttps://doi.org/10.1161/jaha.125.041586
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Discovery of SOX5 as a New Causative Gene for Atrial Fibrillation2025
  2. 2Multiple 4q25 risk variants impair calcium homeostasis and compromise left atrial function2026
  3. 3Single‐Cell Transcriptomics and Mendelian Randomization Analysis Reveal Key Genes in Atrial Fibrillation2026
  4. 4Abstract Thu134: Inherited Variant in MRC2 Causes Cardiac Fibroblast Dysfunction and Increases Atrial Fibrillation Susceptibility2025
  5. 5CEP68/FLRT2: The Potential Druggable Genes For Atrial Fibrillation Identified By Systematic Druggable Genome-Wide Mendelian Randomization2025