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January 9, 2026European Heart Journal - Case ReportsOpen Access

In a patient with hypertrophic cardiomyopathy, a 5.73% five-year risk of sudden cardiac death was assessed, leading to the implantation of a subcutaneous ICD.

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Key result

In a patient with hypertrophic cardiomyopathy, a 5.73% five-year risk of sudden cardiac death was assessed, leading to the implantation of a subcutaneous ICD.

Authors

LGLuis Enrique GomezEAEliana AversaMTMercedes Saenz Tejeira

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Overview

Case report shows risk assessment and personalized management strategies in an athlete with hypertrophic cardiomyopathy, suggesting improved safety during sports activities.

Key Points

  • The aim is to evaluate risk and management approaches in a recreational athlete with hypertrophic cardiomyopathy.
  • Descriptive case report of a 38-year-old recreational athlete diagnosed with hypertrophic cardiomyopathy.
  • Comprehensive assessments using ECG, echocardiography, exercise stress testing, Holter monitoring, and cardiac magnetic resonance.
  • Genetic testing for missense variants in MYBPC3 and risk stratification using ESC and AHA/ACC calculators.
  • Identification of asymmetric non-obstructive HCM with extensive late gadolinium enhancement.
  • Genetic testing revealed two missense variants, with one classified as likely pathogenic.
  • Risk stratification indicated a 5.73% five-year risk of sudden cardiac death, leading to an implanted cardioverter-defibrillator.

Cite This Study

Gomez et al. (2025) studied this question. In a patient with hypertrophic cardiomyopathy, a 5.73% five-year risk of sudden cardiac death was assessed, leading to the implantation of a subcutaneous ICD.

synapsesocial.com/papers/69609567f6dae357db7c14c8https://doi.org/10.1093/ehjcr/ytaf671
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hypertrophic cardiomyopathy: changing the paradigm of exercise prescription and competitive sport participation2025
  2. 2HYPERTROPHIC CARDIOMYOPATHY IN ATHLETES - A LITERATURE REVIEW2025
  3. 3Predictors of recurrent ventricular arrhythmias and the impact of genetic testing in a hypertrophic cardiomyopathy patient cohort at long term follow up2026
  4. 4Arrhythmogenic Right Ventricular Cardiomyopathy in Athletes2026
  5. 5Differentiating an Athlete’s Heart and Cardiomyopathy2026