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December 8, 2025BloodOpen Access

Longitudinal trends (1999–2023) and forecasted mortality (2024–2030) in sepsis-associated mortality among patients with Myelodysplastic Syndromes in the United States.

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Authors

HTHaseeb TareenADAllah DadSBSakshi Bai

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Overview

Analysis shows rising sepsis mortality in Myelodysplastic Syndromes patients, indicating urgent need for improved infection prevention strategies.

Key Points

  • Sepsis mortality in patients with Myelodysplastic Syndromes is projected to increase through 2030, especially among high-risk groups.
  • The overall mortality rate shows significant disparities by gender and race, highlighting urgent health disparities in infection risks.
  • Analysis utilized CDC WONDER data, employing ARIMA and Box-Cox models to forecast age-adjusted mortality rates through 2030.
  • Understanding these trends is crucial for developing targeted strategies to reduce sepsis-related deaths among patients with MDS.

Cite This Study

Tareen et al. (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e53chttps://doi.org/10.1182/blood-2025-2658
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Trends and disparities in myelodysplastic Syndrome–Associated mortality in the u.S. from 1999 to 2020: A population-based study using the CDC wonder database2025
  2. 2Two decades of infectious mortality in Myelodysplastic Syndromes: An analysis from the CDC wonder database2025
  3. 3Temporal trends and demographic disparities in myelodysplastic syndrome-associated mortality in Acute Myeloid Leukemia patients in the United States: A population-based analysis (1999–2023)2025
  4. 4Two-decade trends and future projections of heart failure mortality in Myelodysplastic Syndromes: A nationwide population-based study (1999–2030)2025
  5. 5Blood and filters: The intersection of myelodysplastic syndrome and renal failure in u.S. mortality trends (1999–2023)2025