December 8, 2025BloodOpen Access

Associations between chronic kidney disease, proteinuria, and thrombotic risk in SCD

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Authors

MSMary E. SehlUniversity of California, Los Angeles SWSam WaltersBaltimore City Health Department APAmie PatelUniversity of California, Los Angeles

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Implication

Analysis shows chronic kidney disease and proteinuria increase thrombotic risk in sickle cell disease, indicating a need for targeted prevention strategies.

Key Points

VTE diagnosis significantly associated with chronic kidney disease and proteinuria in sickle cell disease.
Chi-square tests revealed 27% diagnosed with venous thromboembolism among adults with sickle cell disease.
Generalized linear mixed model analysis was used to evaluate demographic covariates and thrombosis risk over time.
Highlights the increased thrombotic risk among patients with chronic kidney disease and proteinuria in sickle cell disease.

Cite This Study

Sehl et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e497 https://doi.org/10.1182/blood-2025-1184

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Implication

Analysis shows chronic kidney disease and proteinuria increase thrombotic risk in sickle cell disease, indicating a need for targeted prevention strategies.

Associations between chronic kidney disease, proteinuria, and thrombotic risk in SCD

Discussion

Member takes

Implication

Key Points

Cite This Study

Associations between chronic kidney disease, proteinuria, and thrombotic risk in SCD

Discussion

Member takes

Implication

Key Points

Cite This Study

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