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December 8, 2025Blood

Direct oral anticoagulation management to address primary and secondary adherence in atrial fibrillation

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Authors

JAJan AndersonEBEllie Balken

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Overview

Quality improvement initiative enhanced adherence to oral anticoagulants in atrial fibrillation, indicating successful pharmacy management strategies.

Key Points

  • Improved primary adherence from 84% to 91% through intervention and education for patients with atrial fibrillation and flutter.
  • Intervention cohort revealed medication adherence rates of 91% primary and 96% secondary, addressing cost-related barriers.
  • Quality improvement initiative utilized pharmacy management to improve adherence to prescriptions of direct oral anticoagulants effectively.
  • Pharmacy team education and cost mitigation strategies proved essential in reducing nonadherence in the patient population.

Cite This Study

Anderson et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e43chttps://doi.org/10.1182/blood-2025-6168
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Implementation evaluation of an inpatient digital dashboard for direct oral anticoagulant surveillance2026
  2. 2Real-world adherence trajectories to direct oral anticoagulants in naive patients with atrial fibrillation in Spain2025
  3. 3Racial disparities and trends in anticoagulant use among ambulatory care patients with atrial fibrillation and atrial flutter in the United States from 2007 to 20192025
  4. 4Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population‐Based Study2025 · 3 citations
  5. 5Anticoagulant adherence and associated complications and readmissions in older valve surgery adults: insights from a retrospective cohort study2026