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September 10, 2025Frontiers in PharmacologyOpen Access

Real-world adherence trajectories to direct oral anticoagulants in naive patients with atrial fibrillation in Spain

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Authors

LLLina María Leguízamo-MartínezMBMartínez BallarinIHIsabel Hurtado

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Overview

Study identifies adherence trajectories to direct oral anticoagulants in atrial fibrillation patients, highlighting factors affecting non-adherence.

Key Points

  • Most patients in Valencia showed high adherence patterns over the follow-up period.
  • Three adherence trajectories emerged in Valencia, while five were identified in Catalonia.
  • Factors such as alcohol use and type of direct oral anticoagulant impacted non-adherence.
  • Socio-economic variables were significant contributors to non-compliance trends in both regions.

Cite This Study

Leguízamo-Martínez et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791c6fhttps://doi.org/10.3389/fphar.2025.1562620
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Direct oral anticoagulation management to address primary and secondary adherence in atrial fibrillation2025
  2. 2Geographic Variation in Persistence of Oral Anticoagulant Treatment Among Patients with Non-Valvular Atrial Fibrillation in the United States2025
  3. 3Anticoagulant adherence and associated complications and readmissions in older valve surgery adults: insights from a retrospective cohort study2026
  4. 4From prescription to outcome: real-world utilization of direct oral anticoagulants in atrial fibrillation across Europe2026
  5. 5Adherence patterns to cardiovascular medications in people with type 2 diabetes mellitus: a retrospective cohort study using group-based trajectory analysis in primary care2025 · 3 citations