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December 8, 2025Blood

Trends in chronic lymphocytic leukemia mortality among patients with pneumonia in the United States (1999–2024): A CDC wonder database analysis

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Authors

SHSyed Tawassul HassanSSShruthi SridharBTBishal Tiwari

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Overview

Analysis shows mortality for CLL patients with pneumonia decreased significantly, indicating ongoing health disparities by race and geography.

Key Points

  • Mortality rates decreased by 68% over 25 years among older adults with CLL and pneumonia — from 21.0 in 1999 to 6.7 in 2024.
  • Analysis of CDC WONDER database revealed significant declines in mortality trends, especially from 2014 to 2021.
  • Older males had a higher mortality rate compared to females, alongside notable disparities based on race and geographic area.
  • Continued public health efforts are crucial to address mortality disparities in CLL patients, particularly among vulnerable populations.

Cite This Study

Hassan et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2fehttps://doi.org/10.1182/blood-2025-8042
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mortality trends of chronic lymphocytic leukemia and pneumonia in the United States (1999–2023): A CDC-wonder analysis2025
  2. 2Trends and disparities in mortality from chronic lymphocytic leukemia in the geriatric population in the United States from 1999 to 2020: A nationwide analysis2025
  3. 3Chronic lymphocytic leukemia mortality among u.S adults aged ≥65: A 56-year trend analysis and demographic disparities2025
  4. 4Uneven gains: Disparities in pneumonia-associated mortality among myeloid leukemia patients in the United States, 1999–2020 — a CDC wonder and joinpoint analysis2025
  5. 5Trends in chronic lymphocytic leukemia mortality among older adults with renal failure in the United States: A 25-year retrospective study.2025