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December 8, 2025Blood

Uneven gains: Disparities in pneumonia-associated mortality among myeloid leukemia patients in the United States, 1999–2020 — a CDC wonder and joinpoint analysis

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Authors

SVSai Sushrutha Mudupula VemulaMSM. SainiAZAbdullah Zia

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Overview

Joinpoint analysis reveals rising pneumonia mortality trends in older adults with myeloid leukemia across demographics.

Key Points

  • Mortality among myeloid leukemia patients with pneumonia increased sharply from 2018 to 2020, highlighting substantial disparities.
  • Joinpoint regression identified distinct mortality trends, showing a significant rise of 12.70% between 2018 and 2020.
  • Analysis of CDC WONDER data from 1999 to 2020 revealed critical disparities across sex, race, and urbanization classifications.
  • Findings underscore the need for targeted prevention efforts and improved resource allocation for high-risk demographic groups.

Cite This Study

Vemula et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e1c7https://doi.org/10.1182/blood-2025-6384
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Also Consider

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  1. 1Mortality trends of sepsis in patients with leukemia in the United States (1999–2020): A CDC wonder database analysis2025
  2. 2Mortality trends of chronic lymphocytic leukemia and pneumonia in the United States (1999–2023): A CDC-wonder analysis2025
  3. 3Trends in chronic lymphocytic leukemia mortality among patients with pneumonia in the United States (1999–2024): A CDC wonder database analysis2025
  4. 4Epidemiological trends in leukemia and heart failure-associated mortality: A CDC wonder database analysis2025
  5. 5Comparative trends in mortality from acute lymphoblastic and Acute Myeloid Leukemia in the United States: A CDC wonder analysis (1999–2020)2025