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December 8, 2025Blood

Geographic and temporal trends in sickle cell disease hospitalizations in New York State

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Authors

PAPrince M. AmegborEPEmmanuel Peprah

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Overview

Retrospective analysis shows rising hospitalization severity and mortality risk in sickle cell disease patients, highlighting racial and socioeconomic disparities.

Key Points

  • Sickle cell disease hospitalization severity and mortality risk increased significantly from 2009 to 2022.
  • Among 42,271 SCD hospitalizations, 10% of patients experienced high mortality risk, particularly in New York City.
  • Retrospective analysis of SPARCS data across New York State revealed disparities in patient outcomes.
  • Findings indicate the need for targeted interventions to address regional and socioeconomic disparities in SCD care.

Cite This Study

Amegbor et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2fahttps://doi.org/10.1182/blood-2025-7960
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Also Consider

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  1. 1Analysis of seasonal variation of sickle cell disease with crisis and associated complication in the United States from 2011 to 2019.2025
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  3. 3Burden and trends of sickle cell disease in the United States: Insights from the global burden of disease study 20212025
  4. 4Paradoxical urban mortality penalty in sickle cell disease: A 20-year national analysis revealing age-dependent disparities2025
  5. 5Disparities in sickle cell disease related mortality in the US-Mexico border region from 1999 to 2020: A CDC wonder Study2025