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December 8, 2025Blood

Detection of iron deficiency anaemia in cirrhosis: Diagnostic utility of ferritin and MCV in a large UK primary care cohort

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Authors

CWCynthia WrightMansfield University AKAlvin KatumbaNHS Blood and Transplant ASAkshay ShahImperial College Healthcare NHS Trust

Discussion

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Implication

Retrospective cohort analysis identifies ferritin and MCV as significant indicators of iron deficiency anaemia in cirrhosis, suggesting diagnostic improvements needed.

Key Points

Iron deficiency anaemia was better identified using ferritin and MCV, revealing critical diagnostic insights.
Among patients, ferritin testing occurred in only 55.7% of individuals with anaemia and a low Hb result.
Analysis of clinical data highlighted significant associations between ferritin levels, MCV readings, and response to oral iron therapy.
Standardized approaches to diagnosing iron deficiency in cirrhosis could improve patient management and outcomes.

Cite This Study

Wright et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2b2 https://doi.org/10.1182/blood-2025-6465

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Implication

Retrospective cohort analysis identifies ferritin and MCV as significant indicators of iron deficiency anaemia in cirrhosis, suggesting diagnostic improvements needed.

Detection of iron deficiency anaemia in cirrhosis: Diagnostic utility of ferritin and MCV in a large UK primary care cohort

Discussion

Member takes

Implication

Key Points

Cite This Study

Detection of iron deficiency anaemia in cirrhosis: Diagnostic utility of ferritin and MCV in a large UK primary care cohort

Discussion

Member takes

Implication

Key Points

Cite This Study

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