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December 8, 2025BloodOpen Access

Mortality patterns due to aplastic anemia in the United States: A retrospective analysis from 1999 to 2023

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Authors

AAAmna AmjadUniversity of Health Sciences LahoreAMAleksandr MarkovBrookdale University Hospital and Medical Center

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Overview

Retrospective analysis finds rising mortality rates in aplastic anemia across demographics, indicating significant inequities.

Key Points

  • Mortality rates from aplastic anemia have been rising, highlighting concerning demographic disparities.
  • The analysis uncovered incidence of 0.6-6.1 per million, showing significant differences across racial groups.
  • Using CDC WONDER data and Joinpoint regression, mortality rates were modeled with their confidence intervals.
  • These findings call for public health strategies to address socioeconomic gaps in aplastic anemia care and treatment.

Cite This Study

Amjad et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e2abhttps://doi.org/10.1182/blood-2025-6460
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aplastic anemia mortality in the United States (1999–2023): Trends, disparities, and public health implications2025
  2. 2Temporal trends in aplastic anemia mortality across u.S. regions (1999–2020)2025
  3. 3Aplastic anemia and substance use: National trends and associations in the United States from 1999-2023- a CDC wonder analysis2025
  4. 4The constant burden-aplastic anaemia as the underlying cause of death in older US adults- half century insights from the CDC wonder database (1968-2023)2025
  5. 5A dangerous convergence: Long-term mortality trends in aplastic anemia and sepsis (1999-2023)2025