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December 8, 2025BloodOpen Access

Social isolation and patient-reported and healthcare utilization in adults with sickle cell disease

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Authors

ACAllen Cheng

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Overview

Cross-sectional analysis demonstrates social isolation exacerbates anxiety and depression in sickle cell disease patients, highlighting needed support.

Key Points

  • Higher social isolation correlates with increased anxiety and depression in sickle cell disease patients.
  • About 37% of participants reported never meaningfully interacting with other sickle cell patients.
  • Analysis of electronic medical records documented emergency department visits and hospitalizations over three months.
  • Identifying and addressing social isolation may improve psychological outcomes in this vulnerable population.

Cite This Study

Allen Cheng (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e213https://doi.org/10.1182/blood-2025-4450
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exploring the relationship between health-related stigma and perceived discrimination among adults with sickle cell disease2025
  2. 2A Mixed-Methods Study to Explore Healthcare Utilization Among Children and Adolescents With Sickle Cell Disease During the COVID-19 Pandemic2025
  3. 3Health-related quality of life measurement in adults with sickle cell disease in steady state: Experience of one French reference center2025
  4. 4Caregiver Well‐Being and Pediatric Healthcare Utilization in Youth With Sickle Cell Disease: The Role of Caregiver and Child Factors2025 · 1 citations
  5. 5Psychiatric comorbidities and the mortality paradox in sickle cell disease: A national inpatient analysis2025