Analysis reveals significant impact of complications on quality of life in adults with sickle cell disease, suggesting improved hydroxyurea compliance may enhance outcomes.
Key Points
Substantial impairment in health-related quality of life was observed in adults with sickle cell disease due to frequent complications.
The study found a strong correlation between the sickle cell self-efficacy scale and the SF-36 scoring system for assessing quality of life.
Univariate and multivariate analyses indicated that recent hospitalization for sickle cell complications significantly impacts quality of life.
Higher compliance to hydroxyurea therapy was linked to improved scores in emotional role functioning, highlighting the importance of treatment adherence.