Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Mortality trends of sepsis in patients with leukemia in the United States (1999–2020): A CDC wonder database analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

AMAnisha ManzoorPDPrachi DawerHJHafiz Muhammad Asif Javed

Discussion

Loading...

Member takes

Overview

National analysis reveals declining sepsis mortality rates in adults with leukemia, indicating the need for targeted therapies and early detection measures.

Key Points

  • Mortality from sepsis in leukemia patients declined overall, while the burden remains significant in minorities and older adults.
  • The analysis identified 63,770 sepsis-related deaths from 1999 to 2020, with a notable decline in age-adjusted mortality rates.
  • Joinpoint regression was employed to assess temporal patterns and calculate annual percent change across different demographics.
  • Efforts must focus on early detection and treatment options for immunocompromised individuals to further lower sepsis-related mortality risks.

Cite This Study

Manzoor et al. (2025) studied this question.

synapsesocial.com/papers/69362f364fa91c937236d38fhttps://doi.org/10.1182/blood-2025-4603
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Uneven gains: Disparities in pneumonia-associated mortality among myeloid leukemia patients in the United States, 1999–2020 — a CDC wonder and joinpoint analysis2025
  2. 2Trends in sepsis-related mortality among patients with Acute Myeloid Leukemia: A 24-year nationwide analysis2025
  3. 3Trends and ARIMA-based forecast of sepsis-related mortality in chronic lymphocytic leukemia (CLL): A u.S. population-based analysis from 1999 to 20302025
  4. 4Mortality Trends and Demographic Disparities Among Patients With Lymphoid Leukemia and Septicemia2025
  5. 5Acute Myeloid Leukemia and sepsis-related mortality in the United States (U.S.) older adults: Nationwide trends and disparities over 25 years (1999 – 2023)2025