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December 8, 2025BloodOpen Access

Presenting features, treatment patterns and predictors of outcomes in AL amyloidosis at a tertirary care cancer centre

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Authors

AAArpit AroraPTPrashant TembhareNPNikhil Patkar

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Overview

Retrospective observational study found delayed diagnosis and renal involvement in patients with AL amyloidosis, indicating a need for better treatment access.

Key Points

  • Nearly 59% of patients with AL amyloidosis achieved good post-induction haematological response and a median follow-up of 18 months was conducted.
  • A total of 93 patients were diagnosed, with organ dysfunction common in 71% due to renal involvement at presentation.
  • Retrospective observational study analyzed clinical features and outcomes using Electronic Medical Records and SPSS software.
  • Identified predictors include renal impairment and lack of haematological response, highlighting potential intervention points.

Cite This Study

Arora et al. (2025) studied this question.

synapsesocial.com/papers/69362f6e4fa91c937236e08chttps://doi.org/10.1182/blood-2025-7501
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IgD-related AL amyloidosis: Clinical features and outcomes2025
  2. 2Mortality & inpatient hospitalizations amongst patients with cardiac light-chain amyloidosis: results from a US administrative claims database2025
  3. 3Diagnostic challenges in systemic light chain( AL) amyloidosis: A retrospective evaluation of biopsy yeild and typing strategies in an Indian tertiary care centre2025
  4. 4Prognostic analysis of newly diagnosed systemic light-chain amyloidosis patients treated with daratumumab2025
  5. 5Outcomes of patients with light-chain amyloidosis after heart transplantation: A single center cohort.2025