December 8, 2025Blood

Descriptive analysis of IgM monoclonal gammopathy of undetermined significance progression events in US veterans

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Progression to malignant disorders occurred in 10.3% of patients diagnosed with IgM monoclonal gammopathy.
Patients were followed for a median duration of 41.6 months, highlighting the long-term observation in this cohort.
Utilizing ICD-10 codes, the analysis categorized various progression events, confirming the clinical relevance of each diagnosis.
The findings suggest low rates of progression to lymphoplasmacytic lymphoma and non-Hodgkin lymphoma warrant further study on mitigating risks.

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Descriptive analysis shows 10.3% progression to malignant disorders in veterans with IgM MGUS, indicating risk factors need exploration.

Tan et al. (2025) studied this question.

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