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December 8, 2025BloodOpen Access

Demographic and laboratory features of monoclonal gammopathy of undetermined significance (MGUS) subtypes in a single-center cohort

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Monoclonal gammopathy showed diverse laboratory features across subtypes, particularly in hemoglobin and beta-2 microglobulin levels.
Among 46 cases, prevalence of IgG MGUS was dominant, while IgM MGUS accounted for 30%, suggesting regional demographic effects.
Patients presented with varied hemoglobin, lactate dehydrogenase, and beta-2 microglobulin levels, influencing clonal activity.
Findings emphasize the need for multicenter studies to refine monoclonal gammopathy characterization in diverse populations.

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Retrospective analysis characterized monoclonal gammopathy variants in patients, highlighting varied lab features and prevalence trends.

Mikulas et al. (2025) studied this question.

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