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December 8, 2025Blood

Real-world outcomes and disparities of ph+ ALL in a Latino population

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Authors

HHHafid De Ruben Calderon Huaycochea

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Overview

Cohort study shows low overall survival in adults with Ph+ ALL, indicating disparities in treatment options in Latin America.

Key Points

  • Overall survival at 7 years was found to be just 12% in patients with Ph+ ALL, highlighting significant mortality risk.
  • Among 162 patients, 31% presented hyperleukocytosis, suggesting a complex disease profile needing thorough management.
  • A retrospective cohort study analyzed patients treated under specific protocols, indicating limited access to stem-cell transplants.
  • These findings indicate the need for better access to tyrosine kinase inhibitors and updated treatment regimens to improve outcomes.

Cite This Study

Hafid De Ruben Calderon Huaycochea (2025) studied this question.

synapsesocial.com/papers/69362f694fa91c937236ded0https://doi.org/10.1182/blood-2025-6843
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  5. 5Overall survival in patients with acute lymphoblastic leukemia in the aya population, treated with modified pediatric chemotherapeutic schemes, a real-life study2025