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December 8, 2025BloodOpen Access

Temporal trends in overall survival among patients with high-risk MDS: Insights from the spanish MDS registry (RESMD)

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Authors

APAna Alfonso PiérolaMAMontserrat ArnánBXBlanca Xicoy

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Overview

Observational analysis shows improved survival in high-risk MDS patients, indicating a positive impact of treatment advances.

Key Points

  • Survival among high-risk MDS patients improved significantly with recent diagnosis, suggesting progress is being made.
  • Median survival increased from 18.7 months to 22.9 months between 2000 and present, though unadjusted results were non-significant.
  • Analysis included over 4000 patients, using multivariable regression to adjust for age and risk factors in survival assessment.
  • The study underlines the need for ongoing advancements in treatment options for this patient population.

Cite This Study

Piérola et al. (2025) studied this question.

synapsesocial.com/papers/69362f4e4fa91c937236d835https://doi.org/10.1182/blood-2025-3868
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