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December 8, 2025Blood

Clinical characteristics and treatment evaluation of T-cell lymphoblastic lymphoma in Chinese children and adolescents：a multicenter clinical study of China-net childhood lymphoma-lbl-2017

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Authors

LFLi FuGeorgia Institute of TechnologyYDYunpeng DaiWestlake UniversityLSLirong SunQingdao University

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Overview

Multicenter clinical study shows therapeutic efficacy and survival rates in children with T-cell lymphoblastic lymphoma, indicating critical prognostic factors.

Key Points

  • Children with T-cell lymphoblastic lymphoma had a 5-year event-free survival rate of 77.1%.
  • A total of 548 newly diagnosed patients participated across 29 centers in China, showing significant clinical features.
  • Analysis involved stratified risk groups based on prognostic factors, notably highlighting those with airway obstruction and tumor lysis syndrome.
  • The results suggest that high-intensity therapies could improve outcomes without increasing CNS relapse incidence.

Cite This Study

Fu et al. (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d73bhttps://doi.org/10.1182/blood-2025-7155
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