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December 5, 2025Frontiers in OncologyOpen Access

Comparative prognosis of pediatric lymphoblastic lymphoma: insights from Chinese and international cohorts

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Authors

LZLuyao ZhangChinese Academy of Medical Sciences & Peking Union Medical CollegeYHYongyan HeSun Yat-sen UniversityWLWei LiuZhengzhou Children's Hospital

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Implication

Analysis reveals no independent prognostic factors for pediatric lymphoblastic lymphoma, suggesting a need for improved treatment approaches.

Key Points

  • Overall survival did not differ significantly between T-LBL and B-LBL subtypes in both cohorts.
  • Statistical analyses included Kaplan-Meier method and multivariate Weibull regression for survival evaluation.
  • Clinical features were assessed across two cohorts: China-LBL and SEER-LBL, revealing disparities in patient demographics.
  • Risk stratification for treatment outcomes requires further investigation into independent prognostic factors and therapy development.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/693231118e51979591dcdf2dhttps://doi.org/10.3389/fonc.2025.1626143
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1T‐cell lymphoblastic lymphoma in children, adolescents and young adults2025 · 8 citations