December 8, 2025BloodOpen Access

Fapi PET/CT as an innovative imaging tool for monitoring bone marrow fibrosis and treatment response in myelofibrosis patients undergoing allogeneic stem cell transplantation

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Authors

VPVictoria Panagiota TFThomas Francke MEMatthias EderUniversity of Freiburg

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Implication

Preliminary analysis shows FAPI PET/CT improves assessment of fibrosis and treatment response in myelofibrosis patients after allogeneic stem cell transplantation.

Key Points

FAPI PET/CT assessments show reductions in fibrotic activity post-transplant, correlating with clinical improvements.
Standardized uptake values from imaging decreased significantly, indicating better monitoring of treatment response.
Evaluation of fibrotic remodeling utilized qualitative and quantitative imaging techniques across key timepoints.
Early findings support FAPI PET/CT as a non-invasive tool for managing myelofibrosis and enhancing patient outcomes.

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Panagiota et al. (2025) studied this question.

synapsesocial.com/papers/69362f444fa91c937236d5f7 https://doi.org/10.1182/blood-2025-4303

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Implication

Preliminary analysis shows FAPI PET/CT improves assessment of fibrosis and treatment response in myelofibrosis patients after allogeneic stem cell transplantation.

Fapi PET/CT as an innovative imaging tool for monitoring bone marrow fibrosis and treatment response in myelofibrosis patients undergoing allogeneic stem cell transplantation

Discussion

Member takes

Implication

Key Points

Cite This Study

Fapi PET/CT as an innovative imaging tool for monitoring bone marrow fibrosis and treatment response in myelofibrosis patients undergoing allogeneic stem cell transplantation

Discussion

Member takes

Implication

Key Points

Cite This Study

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