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December 8, 2025BloodOpen Access

Lymphoma are the most frequent secondary hematologic malignancies following solid tumors: A large cohort study from the german cancer registry nrw

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Authors

ATAmin TurkiIWIna WellmannHKHiltraud Kajüter

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Overview

Large cohort study identifies non-Hodgkin's lymphoma as the most common second malignancy after solid tumors, indicating specific risks in cancer survivorship.

Key Points

  • Aggressive non-Hodgkin's lymphoma is the most common second-diagnosed hematologic malignancy after solid tumors.
  • Among 1,426,752 diagnosed cancer patients, 8,709 cases of secondary hematologic malignancies were observed.
  • Data from the North Rhine-Westphalia Cancer Registry was analyzed, focusing on patients with metachronous hematologic malignancies.
  • The findings highlight the importance of tailored cancer survivorship plans for adolescents and young adults at highest risk.

Cite This Study

Turki et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d50bhttps://doi.org/10.1182/blood-2025-4519
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex-stratified risk of second malignancies in Hodgkin lymphoma survivors: A SEER-based analysis of latency and cancer type.2025
  2. 2Proportion of second hematologic malignancies linked to radiotherapy treatment in adults: A cohort study in the US SEER cancer registries 2001-20222025
  3. 3Cause of non-cancer related death among patients diagnosed with lymphoid neoplasm: A SEER-based study2025
  4. 4Diffuse large B cell lymphoma: A study of second primary malignancies among adults in the United States2025
  5. 5Secondary multiple myeloma and antecedent cancer lineage.2026