Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 9, 2025JCO Oncology Practice

Sex-stratified risk of second malignancies in Hodgkin lymphoma survivors: A SEER-based analysis of latency and cancer type.

View Full Paper
Ask AI
Bookmark
Share

Authors

TMTahir MalikVPVíctor M. Pérez‐GarcíaJMJoseph P. Maslak

Discussion

Loading...

Member takes

Overview

Analysis reveals second primary malignancies in Hodgkin lymphoma survivors, highlighting latency and sex-specific patterns.

Key Points

  • Elevated overall standardized incidence ratios for second malignancies were observed in Hodgkin lymphoma survivors, with notable variations by cancer type and latency.
  • Male and female survivors showed markedly elevated O/E ratios for non-hodgkin lymphoma across all latency periods, particularly within the first year post-hodgkin lymphoma.
  • Respiratory system cancers demonstrated significant elevated risks especially in the first year, highlighting the need for early surveillance in Hodgkin lymphoma survivors.
  • Findings underscore the importance of sex and latency in guiding tailored surveillance strategies for long-term cancer care in Hodgkin lymphoma survivors.

Cite This Study

Malik et al. (2025) studied this question.

synapsesocial.com/papers/68e70db290569dd607ee60f4https://doi.org/10.1200/op.2025.21.10_suppl.547
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lymphoma are the most frequent secondary hematologic malignancies following solid tumors: A large cohort study from the german cancer registry nrw2025
  2. 2Risk of second primary malignancies among CLL survivors across treatment eras: A SEER-based study with racial and ethnic stratification2025
  3. 3Diffuse large B cell lymphoma: A study of second primary malignancies among adults in the United States2025
  4. 4Time-stratified risk of second primary solid malignancies among follicular lymphoma survivors in the United States2025
  5. 5Proportion of second hematologic malignancies linked to radiotherapy treatment in adults: A cohort study in the US SEER cancer registries 2001-20222025