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December 8, 2025Blood

Baseline CD4 count is associated with early mortality in HIV-associated lymphoma: A retrospective cohort study

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Mortality risk markedly increases with baseline CD4 count ≤100 among people living with HIV and lymphoma.
The study reports that progression-free survival is closely tied to immunosuppressive factors rather than solely tumor biology.
Data analysis utilized the Kaplan–Meier and Cox proportional hazards model to elucidate survival outcomes based on immune metrics.
Findings underscore the necessity for targeted cancer care interventions amid social and structural challenges for those with HIV.

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Implication

Retrospective cohort shows that lower baseline CD4 count predicts early mortality in PLWH with lymphoma, highlighting ART's limited role in long-term survival.

Cite This Study

Law et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4c8 https://doi.org/10.1182/blood-2025-3678

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Implication

Retrospective cohort shows that lower baseline CD4 count predicts early mortality in PLWH with lymphoma, highlighting ART's limited role in long-term survival.

Baseline CD4 count is associated with early mortality in HIV-associated lymphoma: A retrospective cohort study

Key Points

Discussion

Implication

Cite This Study

Baseline CD4 count is associated with early mortality in HIV-associated lymphoma: A retrospective cohort study

Key Points

Discussion

Implication

Cite This Study

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