What question did this study set out to answer?

This study aims to compare survival rates in patients with Burkitt lymphoma and diffuse large B cell lymphoma based on HIV status, age, and ethnicity.

December 8, 2025BloodOpen Access

Influence of HIV status, age and ethnicity on survival in patients with burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL): A real-world nationwide database study

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Authors

HMHimil MahadeviaJacksonville College TKTejinder KatariaGuru Gobind Singh Indraprastha University AAAakriti AdhikariUniversity of Missouri–Kansas City

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Implication

Real-world database study shows survival disparities in Burkitt lymphoma and DLBCL based on HIV status, ethnicity, and age groups.

Key Points

This study aims to compare survival rates in patients with Burkitt lymphoma and diffuse large B cell lymphoma based on HIV status, age, and ethnicity.
Analyzed patients diagnosed with Burkitt lymphoma and DLBCL from a nationwide database from 2013-2018.
Identified HIV status using ICD-9 and ICD-10 codes, stratifying patients by age groups and ethnicity.
Calculated overall survival from diagnosis to death or hospice discharge using a multivariate cox regression model.
315 HIV positive patients identified among 10,534 total cases of DLBCL and Burkitt lymphoma.
HIV positive patients with DLBCL had over two-fold higher mortality rate (HR=2.1) compared to HIV negative patients.
African American patients exhibited a 39% increased risk of mortality compared to Caucasian patients with DLBCL.

Cite This Study

Mahadevia et al. (2025) studied this question.

synapsesocial.com/papers/693624d44fa91c937236d06f https://doi.org/10.1182/blood-2025-2726

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Influence of HIV status, age and ethnicity on survival in patients with burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL): A real-world nationwide database study

Discussion

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Implication

Key Points

Cite This Study

Influence of HIV status, age and ethnicity on survival in patients with burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL): A real-world nationwide database study

Discussion

Member takes

Implication

Key Points

Cite This Study

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