Advanced aggressive clinical features may be associated with immune dysfunction in patients with HIV-positive Hodgkin lymphoma in the cART era: a multicenter study from China
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Key Points
HIV-positive Hodgkin lymphoma patients often exhibit more aggressive clinical features compared to HIV-negative patients.
The analysis included 19 HIV-positive and 130 HIV-negative cases, with CD4 counts significantly lower in HIV-positive cases.
The study utilized a retrospective analysis of clinical data from 2014-2024 across four medical centers.
Implications suggest that while HIV-positive patients display advanced disease, treatment outcomes may not differ from those without HIV.
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Implication
Retrospective analysis highlights severe disease characteristics in HIV-positive patients, suggesting immune dysfunction impacts clinical outcomes.