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December 6, 2025Stroke Vascular and Interventional NeurologyOpen Access

Takotsubo Cardiomyopathy Risk Factors and Clinical Outcomes in Aneurysmal Subarachnoid Hemorrhage

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Authors

OAOmar AlwakaaJFJean FiloTFT Fodor

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Overview

Retrospective analysis identifies female sex and vasospasm as risk factors for Takotsubo cardiomyopathy, suggesting it may not affect clinical outcomes in aneurysmal subarachnoid hemorrhage.

Key Points

  • Patients with Takotsubo cardiomyopathy and aneurysmal subarachnoid hemorrhage had higher female prevalence, observed in 93%.
  • The retrospective analysis involved 374 patients, with significant associations found between female sex and TCM.
  • Evaluation used the modified Mayo Clinic criteria and multivariable logistic regression, adjusting for various factors.
  • Findings suggest TCM may be clinically benign in the context of aneurysmal subarachnoid hemorrhage.

Cite This Study

Alwakaa et al. (2025) studied this question.

synapsesocial.com/papers/69337cefb3f947a0a125a29chttps://doi.org/10.1161/svi270000_288
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract Fri090: Recent Evidence on Life-Threatening Arrhythmias in Takotsubo Cardiomyopathy: An Updated Meta-Analysis of Incidence and Outcomes2025
  2. 2Incidence of ischemic stroke in Takotsubo cardiomyopathy patients: a systematic review and meta-analysis2026
  3. 3Emotional Dysregulation and Autonomic Dysfunction in Takotsubo Cardiomyopathy Patients2025
  4. 4Predictors of high-grade atrioventricular block recovery in Takotsubo cardiomyopathy: a systematic review of case reports2026
  5. 5CMR Reveals the Influence of Trigger and Classification on the Myocardial Tissue Response in Takotsubo Syndrome2026