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December 4, 2025International Journal of Molecular SciencesOpen Access

Natural Products as Potential Therapeutic Candidates for Diabetic Kidney Disease: Molecular Mechanisms, Translational Challenges, and Future Prospects

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Authors

LNLihua Ni

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Overview

Preclinical evidence highlights natural products' therapeutic potential for chronic kidney disease, suggesting new treatment strategies.

Key Points

  • Natural Products may improve chronic kidney disease by reducing inflammation and oxidative stress, with promising outcomes.
  • Recent findings indicate that certain natural medicines show beneficial effects against diabetic kidney disease in specific preclinical studies.
  • Assessment of natural products' roles in reducing DKD involves exploring pharmaceutical technologies and their clinical implications.
  • Future translational clinical studies are essential to address the challenges in effectively applying natural product therapies.

Cite This Study

Lihua Ni (2025) studied this question.

synapsesocial.com/papers/6930dc8aea1aef094cca2796https://doi.org/10.3390/ijms262311637
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diabetic kidney disease: from pathogenesis to multimodal therapy–current evidence and future directions2025 · 32 citations
  2. 2Targeting Mitochondrial Dysfunction by Natural Products for the Treatment of Diabetic Kidney Disease2025 · 2 citations
  3. 3Therapeutic potential of natural medicines in diabetic kidney disease: restoring lipid homeostasis via lipophagy modulation2025
  4. 4Advancements in Pharmacotherapy for Diabetic Kidney Disease: A Systematic Review2025 · 7 citations
  5. 5Novel Management Approaches Diabetic Kidney Disease and Chronic Kidney Disease: A Systematic Review2025