December 4, 2025Annals of MedicineOpen Access

Cellular characteristics of the immune microenvironment of colorectal cancer and progress in immunotherapy research

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Immunotherapy shows promise in reshaping treatment approaches for colorectal cancer, focusing on the tumor microenvironment.
Current insights emphasize spatial dynamics within the tumor microenvironment and its impact on immune responses.
Targeting immune-metabolic interactions is crucial for advancing personalized immunotherapy approaches.
This framework may enable new treatment paradigms for colorectal cancer management and improve patient outcomes.

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Analysis reveals the role of targeting immune-metabolic interactions in colorectal cancer, suggesting novel immunotherapy strategies.

Xia et al. (2025) studied this question.

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