What type of study is this?

December 4, 2025Journal of Agricultural and Food Chemistry

Multiomics Analysis Reveals the Therapeutic Effect of GRAS Yeast-Derived 2’-Fucosyllactose in DSS-Induced Colitis

View Full Paper

Ask AI

Bookmark

Authors

MMMengjie MuQingdao University NHNingning HeQingdao University FZFengjuan ZhangGuangxi Normal University

Discussion

Member takes

Implication

Analysis demonstrates the therapeutic effect of 2'-fucosyllactose on ulcerative colitis in mice, implying improvements in gut microbiota balance and inflammation.

Key Points

Colitis symptoms were significantly alleviated by 2'-fucosyllactose, supporting its therapeutic effect.
Treatment improved intestinal barrier function and reduced pro-inflammatory cytokines in the colitis model.
Metabolomic profiling revealed an increase in beneficial metabolites correlated with reduced dysbiosis.
Gene set enrichment analysis indicated 2'-fucosyllactose suppresses the PI3K-Akt signaling pathway, highlighting its immunomodulatory action.

Cite This Study

Mu et al. (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca1f7a https://doi.org/10.1021/acs.jafc.5c08620

View Full Paper

Ask AI

Bookmark

Implication

Analysis demonstrates the therapeutic effect of 2'-fucosyllactose on ulcerative colitis in mice, implying improvements in gut microbiota balance and inflammation.

Multiomics Analysis Reveals the Therapeutic Effect of GRAS Yeast-Derived 2’-Fucosyllactose in DSS-Induced Colitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Multiomics Analysis Reveals the Therapeutic Effect of GRAS Yeast-Derived 2’-Fucosyllactose in DSS-Induced Colitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider