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November 25, 2025The Journal of ImmunologyOpen Access

Soluble sturgeon oil prevents DSS-induced colitis and modulates gut microbiota 9028

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Authors

HLHee Sung LeeJPJi Hyun Park

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Overview

Oral administration of soluble sturgeon oil improves colitis and reduces pro-inflammatory cytokines in mice, suggesting benefits for inflammatory bowel disease.

Key Points

  • This research investigates the effects of soluble sturgeon oil on DSS-induced ulcerative colitis.
  • Used a DSS-induced colitis model in mice
  • Administered soluble sturgeon oil orally
  • Analyzed gut inflammation and weight loss
  • Soluble sturgeon oil reduced colitis severity
  • Decreased pro-inflammatory cytokine levels in dendritic cells and macrophages
  • Improved intestinal microbiota in treated mice

Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/692502dc87af00ed34ac2b2ehttps://doi.org/10.1093/jimmun/vkaf283.2491
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Galactooligosaccharides Promote Gut Barrier Integrity and Exert Anti-Inflammatory Effects in DSS-Induced Colitis Through Microbiota Modulation2025
  2. 2β-Sitosterol improves murine ulcerative colitis by inhibiting the expression of ribosomal proteins and the attempted polarization of type 1 macrophages2025
  3. 3Anti‐Inflammatory, Anti‐Colitis, and Antioxidant Effects of Salidroside against Dextran Sodium Sulfate Induced Ulcerative Colitis in Rats via Inhibition of NF‐κB‐INOS‐No and TLR4‐NF‐κB Signaling Pathways2025
  4. 4Breast-milk Lacticaseibacillus gasseri FN136 alleviates DSS-induced ulcerative colitis through microbiota-independent metabolite–host interactions2025
  5. 5Method of oral delivery affects vitamin C-mediated alleviation of colitis in a mouse model2025