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September 19, 2025Gut Microbes ReportsOpen Access

Method of oral delivery affects vitamin C-mediated alleviation of colitis in a mouse model

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Authors

PBPi Westi BondegaardKKKatja Ann KristensenKKKhorshid Kamguyan

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Overview

Comparative analysis shows vitamin C in peanut butter alleviates ulcerative colitis while water worsens symptoms.

Key Points

  • Vitamin C delivery via peanut butter reduces ulcerative colitis symptoms in mice, enhancing treatment effectiveness.
  • Mice administered vitamin C in peanut butter exhibited a partial reduction in disease activity index compared to DSS-treated controls.
  • Oral delivery methods were assessed using a colitis mouse model induced by dextran sulfate sodium, focusing on treatment outcomes.
  • Findings suggest that certain delivery methods may improve or worsen the effects of vitamin C on gut health.

Cite This Study

Bondegaard et al. (2025) studied this question.

synapsesocial.com/papers/68d436f6713b0b5dfea76689https://doi.org/10.1080/29933935.2025.2549734
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