Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 9, 2025International Journal For Multidisciplinary ResearchOpen Access

Evaluation of Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Type 2 Diabetes Mellitus Using Spectral-Domain Optical Coherence Tomography

View Full Paper
Ask AI
Bookmark
Share

Authors

KBKavya BansalTMTanisha MittalRARajesh Aggarwal

Discussion

Loading...

Member takes

Overview

Cross-sectional study reveals negative correlation of retinal thickness with diabetes duration and HbA1c in type 2 diabetes, indicating potential neurodegenerative biomarker.

Key Points

  • Significant thinning of retinal nerve fiber and ganglion cell layers occurs in type 2 diabetes.
  • Average pRNFL thickness was 90.6 µm in patients without retinopathy, and 86.2 µm with mild retinopathy.
  • Cross-sectional study using spectral-domain optical coherence tomography measured retinal thickness across groups.
  • Findings highlight SD-OCT's role as a biomarker for preclinical retinal neurodegeneration, supporting early intervention.

Cite This Study

Bansal et al. (2025) studied this question.

synapsesocial.com/papers/690fdce2f60c54d04ea3847ehttps://doi.org/10.36948/ijfmr.2025.v07i06.59091
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Longitudinal neural and microvascular changes in type 2 diabetic patients without retinopathy: a 2-year prospective cohort study2025 · 2 citations
  2. 2Evaluation of Peripapillary Retinal Nerve Fiber Layer Thickness and Macular Layer Thickness in Patients with or without Primary Open-Angle Glaucoma with Spectral Domain Optical Coherence Tomography2025
  3. 3Differences in the thickness of various layers of the macular in patients with and without serum vitamin D deficiency in type 2 diabetes mellitus patients without diabetic retinopathy2025
  4. 4Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography-Angiography in Diabetic Patients2024 · 1 citations
  5. 5Early detection of retinal changes in children with diabetes without retinopathy using optical coherence tomography and optical coherence tomography angiography2025