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August 11, 2025Photodiagnosis and Photodynamic TherapyOpen Access

Differences in the thickness of various layers of the macular in patients with and without serum vitamin D deficiency in type 2 diabetes mellitus patients without diabetic retinopathy

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Authors

XMXinyan MaYYYongfeng YangYPYoujin Pan

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Overview

Observational analysis shows reduced retinal thickness in vitamin D deficient diabetes mellitus patients, suggesting potential biomarkers for neurodegeneration.

Key Points

  • Reduced retinal layer thickness is associated with vitamin D deficiency in type 2 diabetes mellitus patients.
  • Significant differences in ganglion cell layer plus inner plexiform layer thickness across all quadrants were reported.
  • Swept-source optical coherence tomography assessed retinal thickness in macular regions, revealing notable reductions.
  • Findings highlight vitamin D deficiency as a possible risk factor for the progression of diabetic retinopathy.

Cite This Study

Ma et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d64770eddhttps://doi.org/10.1016/j.pdpdt.2025.104757
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Vitamin D Deficiency on Peripapillary Retinal Nerve Fiber Layer and Choroidal Thickness: A Cross-Sectional Study2025
  2. 2Evaluation of Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Type 2 Diabetes Mellitus Using Spectral-Domain Optical Coherence Tomography2025
  3. 3Choroidal vascular alterations in diabetic retinopathy and their association with macular microvascular parameters2025 · 4 citations
  4. 4Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography-Angiography in Diabetic Patients2024 · 1 citations
  5. 5Retinal Neuronal Changes and Kidney Dysfunction in Diabetes Mellitus.2025