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November 9, 2025International Journal For Multidisciplinary ResearchOpen Access

Formulation and Evaluation of a Transdermal Patch of Diclofenac Sodium for Sustained Pain Relief

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Authors

HPH. Padmalatha

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Overview

Formulation shows sustained transdermal delivery of Diclofenac sodium for migraine, suggesting improved compliance with patches.

Key Points

  • Sustained transdermal delivery achieved with Diclofenac sodium patches, notably benefiting migraine management.
  • High dose showed drug release of 6.08 mg/cm2 /12 hrs with significant stability over 2 months.
  • Matrix type transdermal patches utilized polymers like HPMC K 15M and DBP as plasticizer in formulation.
  • Supports effective control of migraine, overcoming issues like first-pass metabolism in oral delivery.

Cite This Study

H. Padmalatha (2025) studied this question.

synapsesocial.com/papers/690fdce2f60c54d04ea383e2https://doi.org/10.36948/ijfmr.2025.v07i06.59960
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Formulation Development and Evaluation of Diclofenac Sodium Loaded Sustained Release Pellets2025
  2. 2Formulation and Characterization of Transdermal Patches of Baclofen for Pain Management2025
  3. 3Formulation and In Vitro Characterization of Clonidine HCl Transdermal Drug Delivery System2025
  4. 4Fabrication and Evaluation of Pemetrexed Disodium Transdermal Patches Using a <scp>DoE</scp> Approach2025
  5. 5Formulation and Evaluation of Diclofenac Sodium Matrix Tablets using Tamarind Kernel Gum2025