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November 4, 2025Pediatric Blood & CancerOpen Access

The Association of Sleep Quality, Sociodemographic, and Disease‐Related Factors in Youth Living With Sickle Cell Disease

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Authors

TTTiffany D TuckerUniversity of Alabama at BirminghamDPDakshin PadmanabhanThe Barbara Ann Karmanos Cancer InstituteAAAmmar Saadoon AlishlashUniversity of Alabama at Birmingham

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Implication

Retrospective analysis reveals emergency department visits predict sleep disturbances in youth with sickle cell disease, suggesting interventions are needed.

Key Points

  • Emergency department visits for pain increased the odds of sleep disturbances, indicating a crucial risk factor.
  • Higher fetal hemoglobin and less severe SCD genotype were associated with better oxygen saturation and sleep quality.
  • Retrospective clinical database analysis involved polysomnography and logistic regression to evaluate sleep factors.
  • These findings highlight the need for targeted sleep interventions in youth living with sickle cell disease.

Cite This Study

Tucker et al. (2025) studied this question.

synapsesocial.com/papers/690945348f2297dc13533040https://doi.org/10.1002/pbc.32115
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Health-related quality of life measurement in adults with sickle cell disease in steady state: Experience of one French reference center2025
  2. 2A cross-sectional study on BMI, anemia, and quality of life in children with sickle cell disease2025
  3. 3Caregiver Well‐Being and Pediatric Healthcare Utilization in Youth With Sickle Cell Disease: The Role of Caregiver and Child Factors2025 · 1 citations
  4. 4Association of obstructive sleep apnea with readmission and healthcare utilization in adults with sickle cell disease: A propensity-matched analysis of national readmission data2025
  5. 5Association between parental socioeconomic status and children’s quality of sleep: a cross-sectional study2025 · 3 citations